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BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH CALSCALE:GREGORIAN PRODID:-//WordPress - MECv6.5.5//EN X-ORIGINAL-URL:https://oursymposium.sites.unlv.edu/ X-WR-CALNAME:Office of Undergraduate Research (OUR) Fall 2021 Virtual Undergraduate Research Symposium X-WR-CALDESC: REFRESH-INTERVAL;VALUE=DURATION:PT1H X-PUBLISHED-TTL:PT1H X-MS-OLK-FORCEINSPECTOROPEN:TRUE BEGIN:VEVENT CLASS:PUBLIC DTSTART;TZID=UTC:20211115T000000 DTEND;TZID=UTC:20211120T000000 DTSTAMP:20211027T000000 UID:MEC-46b2644cbdf489fac0e2d192212d206d@oursymposium.sites.unlv.edu CREATED:20211027 LAST-MODIFIED:20211115 PRIORITY:5 TRANSP:OPAQUE SUMMARY:HNSE-P4-5. Regulation of Eye Stem Cells During Regeneration DESCRIPTION:\nhttps://www.youtube.com/watch?v=s34lsuqD58U ( https://www.youtube.com/watch?v=s34lsuqD58U )\n\nIris Nava1\nCindy X. Kha1\nFaculty Mentor: Kelly Ai-Sun Tseng, Ph.D.1\n1College of Science, School of Life Sciences\nABSTRACT\nRegeneration is a response to injury that results in the regrowth of damaged or lost body parts. The mechanisms of this process are poorly understood. Studying a highly regenerative species can further our understanding of the natural regeneration process. The African clawed frog, Xenopus laevis, is an excellent model for studying regeneration as it can regenerate multiple structures including its eyes. Xenopus embryos regenerate eyes within 5 days (Kha et al., 2018). The Vacuolar-ATPase (V-ATPase) is a proton pump that moves protons across the plasma membrane. This pump is important in regulating membrane voltage and has been shown to be important for appendage regeneration. Chemical inhibition of V-ATPase blocked embryonic eye regeneration in Xenopus and resulted in a small regenerate eye. Thus, the function of V-ATPase is required for this process. This project aims to determine the role of V-ATPase during eye regeneration by examining the eye defects caused by V-ATPase inhibition. Insights to the regeneration process can lead to potential medicinal applications.\nThis research was funded by UNLV’s TRIO McNair Scholars Institute, which is housed within UNLV’s Center for Academic Enrichment and Outreach and funded under the TRIO Ronald E. McNair Postbaccalaureate Achievement Program by a grant (P217A170069) from the U.S. Department of Education. \n URL:https://oursymposium.sites.unlv.edu/program/regulation-of-eye-stem-cells-during-regeneration/ ORGANIZER;CN=The Office of Undergraduate Research:MAILTO:our@unlv.edu CATEGORIES:Health & Natural Sciences & Engineering END:VEVENT END:VCALENDAR