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BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH CALSCALE:GREGORIAN PRODID:-//WordPress - MECv6.5.5//EN X-ORIGINAL-URL:https://oursymposium.sites.unlv.edu/ X-WR-CALNAME:Office of Undergraduate Research (OUR) Fall 2021 Virtual Undergraduate Research Symposium X-WR-CALDESC: REFRESH-INTERVAL;VALUE=DURATION:PT1H X-PUBLISHED-TTL:PT1H X-MS-OLK-FORCEINSPECTOROPEN:TRUE BEGIN:VEVENT CLASS:PUBLIC DTSTART;TZID=UTC:20211115T000000 DTEND;TZID=UTC:20211120T000000 DTSTAMP:20211110T000000 UID:MEC-aa6b7ad9d68bf3443c35d23de844463b@oursymposium.sites.unlv.edu CREATED:20211110 LAST-MODIFIED:20211110 PRIORITY:5 TRANSP:OPAQUE SUMMARY:HNSE-O2-4. Evolutionary Analysis of NLR Genes in Metrosideros through Comparative Genomics DESCRIPTION:\n\nSarem Khilji1\nJae Choi2\nFaculty Mentor: Elizabeth Stacy, Ph.D.1\n1College of Science, School of Life Sciences\n2New York University\nABSTRACT\nPlants rely heavily on innate immunity toward pathogens due to the fact that many of them do not contain specialized adaptive immune system cells. In order to mount proper immune responses, plants must come up with several broad defense mechanisms. One such mechanism in these plants, nucleotide-binding domain & leucine-rich repeat (NLR) proteins, are key players when it comes to intracellular immune-related functions. While the biological functions and protein structure of NLR genes are similar across species, variation in NLR gene numbers and sequences among closely related plant taxa can play a key role in diversification and the evolution of reproductive isolating barriers. In this study, we examine variation in NLR genes within Hawaiian Metrosideros (Myrtaceae), an incipient adaptive radiation of woody taxa that show partial isolating barriers. By using NLR annotating software tools, examining the number of NLR genes through code, mapping these genes to their respective chromosomes, and looking at synteny between taxa, we hope to glean insight into the evolution of NLRs in Metrosideros and how variation of these NLR-mediated mechanisms may potentially confer reproductive isolation within taxa. Preliminary results suggest that pubescent Metrosideros taxa may have a greater number of NLR sequences than glabrous taxa while also varying in their distribution across chromosomes. Future synteny analysis will provide a framework for examining variation of these homologous genes and help to establish if gene order is a significant factor of NLR variation among different species.\n URL:https://oursymposium.sites.unlv.edu/program/evolutionary-analysis-of-nlr-genes-in-metrosideros-through-comparative-genomics/ ORGANIZER;CN=The Office of Undergraduate Research:MAILTO:our@unlv.edu CATEGORIES:Health & Natural Sciences & Engineering END:VEVENT END:VCALENDAR