HNSE-P3-5. Electrochemical Damage of Biological Matter
Kevin Ayala Pineda1
Drake Joseph1, 2
Angelica Diaz Tremillo1
Faculty Mentor: Michael Pravica, Ph.D.1
1College of Sciences, Department of Physics and Astronomy
2Howard R. Hughes College of Engineering, Department of Electrical and Computer Engineering
3School of Integrated Health Sciences, Department of Health Physics and Diagnostic Sciences
In the crisis of the coronavirus COVID – 19 pandemic and the urgency of creating quick methods for creating high-quality vaccines, here we present preliminary results that aim at utilizing electrochemistry on a virus with minimal damage to the capsid, and thus target the DNA/RNA to denature the virus. For this project, we worked with biological matter. In this report we discuss the results of DNA and TMV electrochemically damaged in an aqueous solution. The samples were analyzed via Cyclic Voltammetry (CV), NMR, and UV-Vis spectroscopy. The DNA’s fingerprint was significantly altered in all three spectra. Whereas the TMV had significant differences in the CV and NMR but not the UV-Vis spectra.
This research was funded by UNLV’s TRIO McNair Scholars Institute, which is housed within UNLV’s Center for Academic Enrichment and Outreach and funded under the TRIO Ronald E. McNair Postbaccalaureate Achievement Program by a grant (P217A170069) from the U.S. Department of Education.
Dr. Michael Pravica | College of Sciences
Drake Joseph | College of Sciences | Howard R. Hughes College of Engineering
Nicholas Pudar | College of Integrated Health Sciences