HNSE-P4-5. Regulation of Eye Stem Cells During Regeneration
Iris Nava1
Cindy X. Kha1
Faculty Mentor: Kelly Ai-Sun Tseng, Ph.D.1
1College of Science, School of Life Sciences
ABSTRACT
Regeneration is a response to injury that results in the regrowth of damaged or lost body parts. The mechanisms of this process are poorly understood. Studying a highly regenerative species can further our understanding of the natural regeneration process. The African clawed frog, Xenopus laevis, is an excellent model for studying regeneration as it can regenerate multiple structures including its eyes. Xenopus embryos regenerate eyes within 5 days (Kha et al., 2018). The Vacuolar-ATPase (V-ATPase) is a proton pump that moves protons across the plasma membrane. This pump is important in regulating membrane voltage and has been shown to be important for appendage regeneration. Chemical inhibition of V-ATPase blocked embryonic eye regeneration in Xenopus and resulted in a small regenerate eye. Thus, the function of V-ATPase is required for this process. This project aims to determine the role of V-ATPase during eye regeneration by examining the eye defects caused by V-ATPase inhibition. Insights to the regeneration process can lead to potential medicinal applications.
Date
- Nov 15 - 19 2021
- Expired!
Time
- All Day
Labels
- HNSE: Poster Session 4
Organizer
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The Office of Undergraduate Research
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Phone
702-895-4771 -
Email
our@unlv.edu -
Website
http://unlv.edu/our
Speakers
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Cindy X. Kha | College of Sciences
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Dr. Kelly Tseng | College of Sciences
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Iris Nava | College of Sciences
Very interesting study and a great presentation. I shared it with my daughter, who is a senior in high school and hopes to study genetics at UNLV.
That is so awesome! I’m glad you enjoyed my presentation. I also love genetics! I wish your daughter the best of luck with her studies, it’s not always easy but it’s absolutely fascinating!
Iris,
It’s so cool to see that you are still involved with this project! Your poster looks great, and I love the images you’ve included.
Carrie
Hi Carrie! Thank you so much for watching!
Please feel welcomed to leave any questions or comments here. Thank you!